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Updated: Jun 12, 2025

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
Published on: June 6, 2025
Pathogenesis of rheumatoid arthritis: one year in review 2024
Andrea D'Orazio1, Aglaia Lucia Cirillo1, Giulia Greco1
1Immuno-Allergology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.
Abstract:
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterised by joint destruction and extra-articular manifestations. Different cells and soluble components of the innate as well as adaptive immune system actively contribute to the amplification and perpetuation of the inflammatory processes and structural changes. To date, the knowledge on the mechanisms involved in RA pathogenesis is increasingly precise, mainly due to the recent data obtained from studies on genetics and molecular and cellular biology. In this review article we summarised the new insights into RA pathogenesis from original research articles published in the last year.
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