Xenogeneic Bone Block in Lateral Ridge Augmentation: Where Are We Now? A Systematic Review and Meta-analysis.
The International Journal of Oral & Maxillofacial Implants
|September 24, 2024
Summary
Xenogeneic bone blocks (XBBs) show acceptable survival for lateral ridge augmentation, providing adequate bone volume for implants. However, implant survival rates are lower compared to autogenous bone blocks (ABBs).
Area of Science:
- Oral surgery
- Periodontology
- Regenerative medicine
Background:
- Lateral ridge augmentation is crucial for dental implant success.
- Xenogeneic bone blocks (XBBs) offer an alternative to autogenous bone blocks (ABBs).
- Clinical outcomes of XBBs require thorough investigation.
Purpose of the Study:
- To evaluate clinical outcomes of xenogeneic bone blocks (XBBs) in lateral ridge augmentation.
- Focus on bone gain, graft survival, and implant survival rates.
- Compare XBBs with autogenous bone blocks (ABBs) where data allows.
Main Methods:
- Systematic search of PubMed, Embase, and ClinicalTrials.gov up to March 2024.
- Included randomized controlled trials (RCTs) and prospective cohort studies.
- Analyzed horizontal bone gain, resorption, graft, and implant survival rates; assessed study quality using RoB2 and NOS.
Main Results:
- Meta-analysis included 4 RCTs and 5 cohort studies (120 sites, 141 implants).
- Weighted mean horizontal bone gain: 4.38 mm; resorption: 0.85 mm.
- XBBs showed significantly greater horizontal bone gain (0.72 mm difference) versus ABBs in RCTs. Weighted graft survival: 91.3%; implant survival: 84.3%. Histological analysis revealed 11.6-29.8% vital bone and 7.3-21% resorption.
Conclusions:
- Xenogeneic bone blocks (XBBs) provide adequate bone volume and acceptable survival rates for lateral ridge augmentation.
- Implants placed in XBB-augmented sites have a less favorable survival rate compared to those in autogenous bone block (ABB)-augmented sites.
- XBBs are a viable option, but careful patient selection and consideration of implant survival outcomes are necessary.
Keywords:
bone substitutelateral ridge augmentationmeta-analysissystematic reviewxenogeneic bone blockMore Related Videos
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