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Updated: Jun 30, 2026

LAD-Ligation: A Murine Model of Myocardial Infarction
Published on: October 14, 2009
[Libman-Sachs endocarditis and ischemic stroke: A case report]
M C Hoara1, B Simorre2, M R Belabed3
1praticien hospitalier cardiologie, Centre Hospitalier 2 rue Valentin Haüy 34500 Béziers, France.
Abstract:
Libman-Sacks endocarditis is a rare cardiac manifestation of anti-phospholipid syndromes, in which non-infectious thrombotic vegetations are found on the heart valves. Most patients are asymptomatic whereas the risk of thromboembolism is considerable. Diagnostic work-up is based on questioning and clinical examination data looking for extracardiac signs, biological data and also on imaging, and, above all, echocardiography. We report the case of a 47-year-old female patient with no known history who is admitted to hospital with paresthesia of the right hemi-body associated with dysarthria. Cerebral CT scan confirms a paraventricular ischemic stroke. The etiological work-up for stroke is negative except the transesophageal echocardiogram which reveals mitral valve vegetations. Further investigations lead to the diagnosis of Libman-Sacks endocarditis. Treatment with Coumadin is started, with a target INR of between 2 and 3, as recommended. The clinical course was favourable, with stable lesions on transoesophageal echocardiography carried out later.
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