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Palmoplantar pustulosis and smoking
British Medical Journal (Clinical Research Ed.)
|September 28, 1985
Summary
Smoking is significantly more common in individuals with palmoplantar pustulosis, a chronic skin condition. This finding suggests smoking may play a role in the development or exacerbation of this inflammatory skin disease.
Area of Science:
- Dermatology
- Epidemiology
- Public Health
Background:
- Palmoplantar pustulosis (PPP) is a chronic inflammatory skin condition affecting the palms and soles.
- The etiology of PPP remains incompletely understood, necessitating further investigation into potential contributing factors.
Purpose of the Study:
- To investigate the association between smoking and palmoplantar pustulosis.
- To explore potential links between smoking habits and the prevalence of PPP.
Main Methods:
- A multicentre case-control study was conducted.
- The study included 216 patients diagnosed with palmoplantar pustulosis and 626 controls with various dermatoses.
Main Results:
- A considerably higher prevalence of smoking was observed in the group of patients with palmoplantar pustulosis compared to the control group.
- This finding indicates a statistically significant association between smoking and PPP.
Conclusions:
- Smoking appears to be an important risk factor for palmoplantar pustulosis.
- Smoking may influence the inflammatory pathways involved in the pathogenesis of this skin disease.