Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Role of Hippocampus in Memory

Role of Hippocampus in Memory

The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...

Functional Brain Systems: Limbic System

Functional Brain Systems: Limbic System

The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep...

Role of Cerebellum and Prefrontal Cortex in Memory

Role of Cerebellum and Prefrontal Cortex in Memory

The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...

Diencephalon: Thalamus and Information Relay

Diencephalon: Thalamus and Information Relay

The thalamus, often called “the gateway to the cerebral cortex,” is vital in processing and directing sensory and motor signals throughout the brain. Almost all inputs destined for the cerebral cortex, except for olfactory signals, are relayed through the thalamus. The thalamus is a sophisticated relay station, channeling information from various brain regions to the cerebral cortex, as well as a filter, prioritizing certain signals over others based on current physiological...

Hierarchy of Motor Control

Hierarchy of Motor Control

The hierarchy of motor control refers to the different levels of organization and processing involved in controlling movement in the body. These levels range from higher cortical areas involved in planning and decision-making to lower spinal cord reflexes that respond automatically to external stimuli.

Brainstem

Brainstem

The brainstem, located inferior to the brain and superior to the spinal cord, serves as a bridge between the cerebrum and the spinal cord. It plays a vital role in relaying information and controlling critical life functions. It comprises three primary regions: the midbrain, pons, and medulla oblongata.
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Motor and Cognitive Sequence Tasks Exhibit Different Ramping Patterns in Parietal and Prefrontal Cortices.

Journal of cognitive neuroscience·2025

Same author

Ramping dissociates motor and cognitive sequences in the parietal and prefrontal cortices.

bioRxiv : the preprint server for biology·2024

Same author

Cortical Patterns Shift from Sequence Feature Separation during Planning to Integration during Motor Execution.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2023

Same author

Competitive state of movements during planning predicts sequence performance.

Journal of neurophysiology·2021

Search research articles

Related Experiment Video

Updated: Jun 12, 2025

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Published on: January 26, 2024

The Hippocampus Preorders Movements for Skilled Action Sequences.

Rhys Yewbrey^1,2, Katja Kornysheva^3,2

¹Centre for Human Brain Health, School of Psychology, University of Birmingham, Birmingham B15 2TT, United Kingdom.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience

|September 24, 2024

Summary

This summary is machine-generated.

The hippocampus, not just for declarative memory, helps plan and order movements for skilled actions. This challenges traditional memory roles and aids understanding of neurodegenerative disorders.

Keywords:

MVPA cerebellum hippocampus motor control motor planning striatum

More Related Videos

Acquisition of a High-precision Skilled Forelimb Reaching Task in Rats

Acquisition of a High-precision Skilled Forelimb Reaching Task in Rats

Published on: June 22, 2015

A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat

A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat

Published on: April 24, 2009

Related Experiment Videos

Last Updated: Jun 12, 2025

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function

Published on: January 26, 2024

Acquisition of a High-precision Skilled Forelimb Reaching Task in Rats

Acquisition of a High-precision Skilled Forelimb Reaching Task in Rats

Published on: June 22, 2015

A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat

A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat

Published on: April 24, 2009

Area of Science:

Neuroscience
Cognitive Neuroscience
Motor Control

Background:

The basal ganglia-thalamo-cerebellar network is crucial for procedural skill learning.
Recent research highlights the hippocampus's role in well-trained motor actions.
The exact function of subcortical areas in skilled motor sequence control remains unclear.

Purpose of the Study:

To investigate the role of subcortical brain regions in skilled motor sequence control.
To differentiate the functions of these regions during planning and execution phases.
To explore the information content of neural activity in these areas.

Main Methods:

Functional magnetic resonance imaging (fMRI) was used to analyze brain activity.
Participants performed learned four-finger press sequences from memory.
BOLD activity and its informational content were examined in subcortical regions.

Main Results:

Increased BOLD activity was observed in striatal, thalamic, and cerebellar regions during sequence execution.
This widespread activity did not encode specific motor sequence information.
Hippocampal activity increased during planning and predicted the upcoming movement order.

Conclusions:

The hippocampus plays a role in preordering movements for skilled action sequences.
This suggests a higher-order control function for flexible motor retrieval.
Findings challenge traditional memory classifications and have implications for neurorehabilitation.