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Updated: Jun 12, 2025

A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting
Published on: March 9, 2017
Development of chemiluminescent systems and devices for analytical applications
Zhiyong Dong1,2, Fangxin Du3, Saima Hanif4
1State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, PR China.
Abstract:
Chemiluminescence (CL) refers to the light-emitting phenomenon resulting from chemical reactions. Due to its simplicity in terms of instrumentation and high sensitivity, CL plays a critical role in analytical chemistry and has developed rapidly in recent years. In this review, we discuss the efforts made by our group in the field of CL. This includes exploring new luminophores that function under neutral pH conditions, developing oxidant- and reactive oxygen species-based coreactants (e.g. artemisinin and thiourea dioxide) for luminol and lucigenin CL, utilizing nanomaterial-based CL signal amplification and employing innovative ultrasound devices for CL and their analytical applications. We discussed the CL amplification mechanisms of these systems in detail. Finally, we summarize the challenges and prospects for the future development of CL.
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