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Correlation between macular sensitivity and kidney function in patients with diabetes
Antoaneta Adžić Zečević1,2, Valentina Vujović Kalinić3, Zorica Potpara4
1Department of Medicine, Faculty of Medicine, University of Montenegro, Kruševac bb, Podgorica, Montenegro.
European Journal of Ophthalmology
|September 25, 2024
Summary
Kidney function in diabetic patients is linked to macular sensitivity, even with normal vision. Microperimetry can detect early diabetic retinopathy and aid in monitoring kidney health.
Area of Science:
- Ophthalmology
- Nephrology
- Diabetology
Background:
- Diabetic retinopathy is a leading cause of vision loss.
- Kidney function is often affected in patients with diabetes.
- Macular sensitivity is a key indicator of retinal health.
Purpose of the Study:
- To investigate the correlation between kidney function and macular sensitivity in diabetic patients.
- To assess the utility of microperimetry in detecting early signs of diabetic complications.
Main Methods:
- A cross-sectional study involving 30 diabetic patients (58 eyes).
- Full-threshold microperimetry of the central 10° macula was performed.
- Pearson correlation was used to analyze the relationship between macular sensitivity and kidney function markers (GFR, microalbuminuria), blood glucose, and HbA1c.
Main Results:
- A significant positive correlation was found between Glomerular Filtration Rate (GFR) and macular sensitivity in both male and female participants.
- No statistically significant correlation was observed between macular sensitivity and microalbuminuria, blood glucose, or HbA1c.
- Impaired kidney function was associated with decreased macular sensitivity, despite normal visual acuity.
Conclusions:
- Microperimetry can detect reduced macular sensitivity in diabetic patients with impaired kidney function, even before visual acuity is affected.
- This highlights the importance of microperimetry in the preventative care and early detection of diabetic retinopathy.
- Microperimetry may serve as a valuable auxiliary tool for monitoring kidney function in diabetic individuals.
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