Mutual Influence Between Allergic Rhinitis and Sleep: Factors, Mechanisms, and interventions-A Narrative Review

Area of Science:

• Immunology
• Sleep Medicine
• Clinical Research

Background:

• Allergic rhinitis (AR) frequently co-occurs with sleep disorders like insomnia.
• This interaction creates a detrimental cycle, worsening both nasal and sleep symptoms.
• Severe cases can lead to psychological and neurological issues, complicating patient care.

Purpose of the Study:

• To review and synthesize current research on the relationship between allergic rhinitis and sleep disorders.
• To explore the influencing factors and potential mechanisms underlying this association.
• To identify potential diagnostic biomarkers and therapeutic targets for AR-related sleep disturbances.

Main Methods:

• Systematic literature search using keywords 'allergic rhinitis' and 'sleep disorders'.
• Analysis and summarization of findings from relevant studies.
• Evaluation of the correlation, interaction, and potential mechanisms between AR and sleep disorders.

Main Results:

• A significant correlation exists between allergic rhinitis and various sleep disorders.
• The interplay between AR and sleep involves complex mechanisms requiring further investigation.
• Current therapeutic options for AR-associated sleep issues are insufficient.

Conclusions:

• Understanding the AR-sleep disorder nexus is critical for clinical practice.
• Further research is needed to elucidate underlying mechanisms and identify novel therapeutic targets.
• This review provides a foundation for developing improved diagnostic and treatment strategies for patients with comorbid AR and sleep disorders.