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Diagnostic Value of Chest Computed Tomography Scan for Identification of Foreign Body Aspiration in Children: A
Babak Goodarzy1, Erfan Rahmani2, Mehrdad Farrokhi3
1School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Insights
Chest computed tomography (CT) scans effectively diagnose foreign body aspiration (FBA) in children, a critical pediatric emergency. This meta-analysis confirms CT
Area of Science:
- Pediatric Emergency Medicine
- Diagnostic Imaging
- Radiology
Background:
- Foreign body aspiration (FBA) is a significant pediatric emergency with high morbidity and mortality risks.
- Accurate and timely diagnosis is crucial for effective management of FBA in children.
Purpose of the Study:
- To systematically review and meta-analyze the diagnostic value of chest computed tomography (CT) for identifying FBA in pediatric patients.
- To quantify the accuracy of chest CT scans in the diagnosis of foreign body aspiration in children.
Main Methods:
- A systematic literature search was conducted across major databases (Medline, Scopus, Web of Science) up to May 2024.
- Included studies were assessed for quality using the QUADAS-2 tool.
- Meta-analysis techniques were employed to pool diagnostic accuracy metrics.
Main Results:
- The systematic search identified 7203 articles.
- Pooled sensitivity for chest CT in FBA detection was 0.99 (95% CI: 0.98-0.99) and pooled specificity was 0.97 (95% CI: 0.96-0.98).
- The area under the SROC curve was 0.98, indicating high diagnostic performance.
Conclusions:
- Chest CT scans demonstrate high diagnostic value for identifying foreign body aspiration in children.
- Despite study heterogeneity, CT imaging is a reliable tool for suspected pediatric FBA cases.
Introduction:
Foreign body aspiration (FBA) is a common, life-threatening pediatric emergency and was shown to be associated with high risk of morbidity and mortality. This systematic review and meta-analysis aimed to investigate the diagnostic value of chest computed tomography (CT) scan for identification of FBA in children.
Methods:
From inception to May 2024, a systematic search was carried out across multiple databases including Medline, Scopus, and Web of Science, considering published papers in English language. Quality assessment of the included studies was performed using seven domains of Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2).
Results:
The systematic literature search yielded 7203 articles. The pooled sensitivity and specificity of chest CT scan for identification of FBA were 0.99 (95% CI: 0.98-0.99) and 0.97 (95% CI: 0.96-0.98), respectively. The pooled positive likelihood ratio was 10.12 (95% CI: 4.59-22.20), and pooled negative likelihood ratio was 0.05 (95% CI: 0.02-0.1). Furthermore, the area under the summarized receiver operating characteristic (SROC) curve was 0.98.
Conclusion:
Our meta-analysis revealed that despite high heterogeneity, in the diagnostic characteristics of chest CT scan among studies, it has high diagnostic value in identifying FBA in suspected pediatric cases.
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