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Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
Subacute thyroiditis after receiving the COVID-19 vaccine
Yingshuo Zhong1, Chang Di1, Xiaohui Yang1
1Department of Endocrinology, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning, China.
Abstract:
Since the emergence of the coronavirus disease 2019 (COVID-19). Several autoimmune and subacute thyroiditis (SAT) cases are on the rise all over the world. COVID-19 vaccine-associated SAT cases have also been reported. In this article, we present our data on 5 vaccine-associated SAT cases. We evaluated the type of vaccine received, the time between vaccination and the onset of SAT symptoms, laboratory findings, treatments administered, and response to treatment. The age of patients ranged from 31 to 43 years old. Three (60 %) patients had been diagnosed as SAT after the first dose, and tow (40 %) after the second dose. Patients' symptoms appeared approximately 25.2 days (2-44) after vaccination. Subacute thyroiditis occurring after COVID-19 vaccination is rare, we hope practitioners should be early aware of post-vaccine SAT, that can improve clinical evolution and outcome.
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