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Isolation of Cognate RNA-protein Complexes from Cells Using Oligonucleotide-directed Elution
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Unveiling the DHX15-G-patch interplay in retroviral RNA packaging

Alžběta Dostálková1, Ivana Křížová1, Petra Junková2,3

  • 1Department of Biotechnology, University of Chemistry and Technology, 166 28 Prague, Czech Republic.

Proceedings of the National Academy of Sciences of the United States of America
|September 25, 2024
PubMed
Summary

Mason-Pfizer monkey virus (M-PMV) hijacks the cellular RNA helicase DHX15 for replication. This virus recruits DHX15 to the cytoplasm, essential for viral genome packaging and infectivity.

Keywords:
DEAH-box RNA helicaseDHX15G-patchgRNA packagingretrovirus

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