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Related Experiment Video

Updated: Jun 12, 2025

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants

Published on: March 29, 2018

Cost-Effectiveness of Managing MIH Teeth.

Renata Paz Leal Pereira¹, Ana Clara Falabello de Lucca¹, Maria Carolina Costa Prestes¹

¹Department of Orthodontics and Pediatric Dentistry, Faculty of Dentistry, University of São Paulo, São Paulo, Brazil.

Monographs in Oral Science

|September 25, 2024

Summary

Economic evaluations for molar incisor hypomineralisation (MIH) are scarce. Further research is needed to assess cost-effectiveness, especially for preventive strategies, to guide optimal patient treatment.

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Area of Science:

Dental Public Health
Health Economics
Pediatric Dentistry

Background:

Molar incisor hypomineralisation (MIH) presents numerous therapeutic challenges.
The cost-effectiveness of various MIH management strategies remains largely underexplored.
Economic evaluations are vital for optimizing treatment decisions in MIH.

Purpose of the Study:

To systematically review the existing literature on the economic evaluations of therapeutic approaches for molar incisor hypomineralisation.
To synthesize current evidence on the costs and cost-effectiveness of MIH management.
To identify gaps and future research directions in the economic assessment of MIH treatments.

Main Methods:

Systematic literature searches were conducted.
A two-stage selection process identified relevant studies.
Eleven studies were included and categorized based on cost information provided (assumptions, cost collection, cost-effectiveness evaluations).

Main Results:

The economic evidence base for MIH management is currently limited and in its early stages.
A database of costs associated with MIH therapeutic approaches was compiled.
Evidence synthesis highlighted directions for decision-making, emphasizing economic outcomes, generalizability, and patient/professional preferences.

Conclusions:

There is a significant need for more comprehensive economic evaluations in MIH management.
Future research should prioritize investigating the cost-effectiveness of preventive strategies for early-stage MIH to avoid costly, complex treatments.
Integrating economic outcomes into evidence-based practice is crucial for informed decision-making in MIH care.