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Updated: Jun 12, 2025

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
Ischemic events are infrequent in patients with ovarian hyperstimulation syndrome
Alison Seitz1, Alis J Dicpinigaitis2, Cenai Zhang2
1University of Washington, Department of Neurology, Seattle, USA.
Background:
Case reports describe arterial thrombosis including ischemic stroke associated with severe ovarian hyperstimulation syndrome (OHSS), but the prevalence of major ischemic events during or shortly after OHSS is unknown.
Methods:
Using publicly available administrative datasets in the United States between 2015 and 2020, we conducted two separate cross-sectional studies of patients with OHSS. We included all patients with OHSS. Our study outcome was any hospitalization for acute ischemic stroke, acute myocardial infarction, cerebral venous sinus thrombosis, pulmonary embolism, or acute deep venous thrombosis during the index hospitalization or within 90 days of OHSS diagnosis.
Results And Conclusions:
We found very few major ischemic events in patients with OHSS.
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