Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Disorders of Leukocytes01:27

Disorders of Leukocytes

903
Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...
903

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

"Large-Scale and Local Functional Connectivity Changes Following Psilocybin Administration in Methamphetamine Use Disorder.

AJNR. American journal of neuroradiology·2026
Same author

Neuroradiological features across major psychiatric disorders and behavioral variant of Alzheimer's disease: a concise multimodal synthesis.

Psychoradiology·2026
Same author

Neuroinfectious diseases in 2025: pathogens old and new.

The Lancet. Neurology·2025
Same author

Venous manometry triage in refractory idiopathic intracranial hypertension: imaging and criteria validity.

Journal of neurointerventional surgery·2025
Same author

Reliability and Spatial Consistency of MR Diffusion Tensor Imaging Measures Along the Cerebral Perivascular Space.

Journal of neuroimaging : official journal of the American Society of Neuroimaging·2025
Same author

Higher levels of cell-associated HIV-1 RNA transcripts predict risk of viral blips: implications for clinical management and cure research.

AIDS (London, England)·2025
Same journal

Preface.

Handbook of clinical neurology·2026
Same journal

Foreword.

Handbook of clinical neurology·2026
Same journal

Fundus autofluorescence imaging.

Handbook of clinical neurology·2026
Same journal

The electroretinogram as a means to study the physiology of the retina.

Handbook of clinical neurology·2026
Same journal

Adaptive optics scanning light ophthalmoscopy.

Handbook of clinical neurology·2026
Same journal

Modeling the human retina in a dish: Advances and future directions.

Handbook of clinical neurology·2026
See all related articles

Related Experiment Video

Updated: Jun 12, 2025

A Model for Epilepsy of Infectious Etiology using Theiler's Murine Encephalomyelitis Virus
05:33

A Model for Epilepsy of Infectious Etiology using Theiler's Murine Encephalomyelitis Virus

Published on: June 23, 2022

2.7K

Infectious leukoencephalopathies.

David Jakabek1, Joga Chaganti2, Bruce James Brew3

  • 1Department of Neurology, St. Vincent's Hospital, Sydney, NSW, Australia; University of New South Wales, Sydney, NSW, Australia.

Handbook of Clinical Neurology
|September 25, 2024
PubMed
Summary
This summary is machine-generated.

Infectious agents can cause leukoencephalopathy, a white matter disease, with varied timelines and outcomes. Early diagnosis and treatment are crucial for better outcomes in these infections.

Keywords:
BacterialEBVEncephalitisHIVHSVJC virusLeukoencephalitisProtozoalVZVViral

More Related Videos

Isolation of Brain-infiltrating Leukocytes
06:44

Isolation of Brain-infiltrating Leukocytes

Published on: June 13, 2011

19.1K
A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
04:23

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

6.5K

Related Experiment Videos

Last Updated: Jun 12, 2025

A Model for Epilepsy of Infectious Etiology using Theiler's Murine Encephalomyelitis Virus
05:33

A Model for Epilepsy of Infectious Etiology using Theiler's Murine Encephalomyelitis Virus

Published on: June 23, 2022

2.7K
Isolation of Brain-infiltrating Leukocytes
06:44

Isolation of Brain-infiltrating Leukocytes

Published on: June 13, 2011

19.1K
A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
04:23

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

6.5K

Area of Science:

  • Neurology
  • Infectious Diseases
  • Radiology

Background:

  • Leukoencephalopathy can result from various infectious agents, presenting with diverse clinical courses, from rapid to chronic.
  • Infections affecting the white matter impact both immunocompetent and immunodeficient individuals globally.
  • Some infectious leukoencephalopathies have high mortality rates, while others are treatable if identified early.

Purpose of the Study:

  • To comprehensively review viral, bacterial, and protozoal infections causing leukoencephalopathy.
  • To elucidate the clinical presentations, epidemiology, and pathophysiological mechanisms of these infections.
  • To detail diagnostic methods, MRI features, and treatment strategies for infectious leukoencephalopathies.

Main Methods:

  • Literature review focusing on infectious causes of leukoencephalopathy.
  • Analysis of clinical presentations, epidemiology, and pathogenesis.
  • Discussion of diagnostic tests, MRI findings, and therapeutic approaches.

Main Results:

  • Infectious agents cause leukoencephalopathy with variable clinical courses and geographic distributions.
  • Pathophysiological mechanisms leading to white matter injury are diverse among different pathogens.
  • MRI imaging plays a critical role in diagnosing and differentiating infectious leukoencephalopathies.

Conclusions:

  • Infectious leukoencephalopathies represent a significant diagnostic challenge with potentially severe outcomes.
  • Understanding the specific infectious agent, its presentation, and imaging features is key to timely management.
  • Prompt diagnosis and targeted treatment can improve prognosis for certain treatable infectious leukoencephalopathies.