Related Experiment Video
Updated: Jun 12, 2025
10:26
A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Published on: June 2, 2015
17.2K
Extended anticoagulation after venous thromboembolism.
Rasmus Laursen1, Hanne M Søndergaard1, Pia Børding1
1Department of Cardiology, Regional Hospital Viborg, Denmark.
Danish Medical Journal
|September 26, 2024
Summary
Extended anticoagulation is common for venous thromboembolism (VTE) patients, especially those at high or intermediate risk. Most patients in this real-world clinic received extended treatment, with non-vitamin K antagonist oral anticoagulants being the preferred choice.
Area of Science:
- Medicine
- Cardiology
- Hematology
Background:
- Venous thromboembolism (VTE) recurrence risk varies by index event.
- Extended anticoagulation is recommended for high-risk and considered for intermediate-risk VTE patients.
- Clinical practice for extended anticoagulation in VTE needs further insight.
Purpose of the Study:
- To investigate the clinical practice of extended anticoagulation for VTE patients.
- To analyze the decision-making process for extending anticoagulation based on recurrence risk.
Main Methods:
- Retrospective study of VTE patients from January 2020 to June 2021.
- Patients categorized into low (<3%), intermediate (3-8%), and high (>8%) recurrence risk groups.
- Treatment decisions made in a multidisciplinary VTE clinic.
Main Results:
- 315 VTE patients analyzed; 58.7% had intermediate recurrence risk.
- 80.3% of all eligible patients received extended anticoagulation treatment.
- Extended therapy use was 97.9% for high-risk, 82.7% for intermediate-risk, and 15.2% for low-risk patients.
- Non-vitamin K antagonist oral anticoagulants (82.2%) were preferred for extended therapy.
Conclusions:
- The majority of VTE patients in this clinic transitioned to extended anticoagulation.
- Extended treatment was widely adopted across different risk categories.
- Further research is needed on patient and physician preferences influencing treatment decisions.
Related Concept Videos
01:29Venous Thrombosis III: Interprofessional Care
3
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
3
01:30Venous Thrombosis IV: Nursing Management
3
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
3
01:18Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
1.2K
Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
1.2K
01:30Venous Thrombosis I: Introduction
3
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
3
01:30Anticoagulant Drugs: Low-Molecular-Weight Heparins
649
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
649
01:20Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
3
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
3