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Antibiogram development for Australian residential aged care facilities.

Dipti Khatri¹, Nazanin Falconer², Sonali Coulter³

¹UQ Centre for Health Service Research (CHSR), Faculty of Medicine, The University of Queensland, Woolloongabba, QLD, Australia.

Infection Control and Hospital Epidemiology

|September 26, 2024

Summary

Developing antibiograms for residential aged care facilities (RACFs) is feasible using extended 3-year data or pooled data from nearby facilities. This provides crucial local antibiotic resistance insights for better empirical antibiotic prescribing.

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Area of Science:

Infectious Diseases
Antimicrobial Resistance
Healthcare Epidemiology

Background:

Antibiograms are essential for guiding empirical antibiotic selection.
Residential aged care facilities (RACFs) require local antibiotic resistance data.
Developing facility-specific antibiograms presents challenges due to limited data.

Purpose of the Study:

To assess the feasibility of creating antibiograms for RACFs.
To explore methods for improving antibiogram development in RACFs.

Main Methods:

Retrospective observational study of culture and sensitivity data from nine RACFs in Queensland, Australia (2020-2022).
Data analyzed using WHONET software according to CLSI-M39 guidelines.
Explored extending the time period and pooling data from geographically similar RACFs.

Main Results:

Annual antibiograms were not feasible for individual RACFs due to low culture counts (<30).
Extending the time period to three years improved antibiogram feasibility for *Escherichia coli* and *Staphylococcus aureus*.
Pooled annual antibiograms were feasible when combining data from closely located RACFs.

Conclusions:

Extended time-period antibiograms offer RACF-specific urinary and skin/soft tissue resistance data.
Pooled syndromic antibiograms can be generated annually, potentially being the preferred option.
RACF-specific antibiograms can be developed without private pathology provider input.