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Updated: Jun 12, 2025

Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes
Published on: September 27, 2018
Refractory Cryptoglandular Perianal Abscess and Fistulas Due to Mycobacterium avium Infection in an Immunocompetent
Hannah Y Lyons1, Jackson R Brunner1, Markos Mardourian1
1Division of Infectious Diseases and Global Medicine, College of Medicine, University of Florida, Gainesville, USA.
Abstract:
Mycobacterium avium is a slow-growing nontuberculous mycobacterium (NTM) requiring prolonged treatment with multiple antimicrobials. It primarily affects immunocompromised patients and causes infection of the respiratory tract, skin, and soft tissue. While enteric carriage of M. avium has been reported, it has not been associated with clinical infection in immunocompetent hosts. To our knowledge, this is the first case report of a perirectal abscess caused by primary M. avium infection in an otherwise healthy patient and indicates the importance of considering NTMs as causative organisms in intraabdominal and enteric abscesses even among immunocompetent individuals when multiple courses of antibiotics are ineffective.
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