Clinical Profile of Neurodevelopmental Disorders in Children at a Tertiary Care Center

Mridu Bahal1, Vineeta Pande1, Shradha Salunkhe1

  • 1Pediatrics, Dr. D.Y. Patil Medical College, Hospital and Research Center, Dr. D.Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.

Cureus
|September 26, 2024
PubMed

Insights

Neurodevelopmental disorders (NDDs) affect 9.1% of children, with intellectual disability and ADHD being most common. Children from low-income backgrounds are disproportionately affected, highlighting a need for increased awareness and resources.

Area of Science:

  • Pediatrics
  • Neuroscience
  • Public Health

Background:

  • Neurodevelopmental disorders (NDDs) are complex conditions influenced by genetic and environmental factors, impacting childhood development and functioning.
  • NDDs include ADHD, intellectual disability, autism spectrum disorders (ASDs), and sensory/motor impairments, with vulnerable populations in low-income settings.
  • Limited data exists on NDD prevalence in developing countries, particularly in India's diverse population.

Purpose of the Study:

  • To determine the prevalence and identify risk factors of neurodevelopmental disorders in children.
  • To analyze the types and co-occurrence of NDDs in a pediatric tertiary care setting.

Main Methods:

  • A prospective study involving 1000 children aged six months to nine years.
  • Data collection included patient demographics, clinical findings, and medical history using a pre-designed pro forma.
  • Statistical analysis was performed to evaluate prevalence and risk factors.

Main Results:

  • 9.1% of children (91 out of 1000) were diagnosed with NDDs.
  • The highest prevalence was observed in the 3-4 year age group, with a male predominance (3:1 ratio).
  • Intellectual disability (20.9%), ADHD (17.6%), and vision impairment (14.3%) were the most frequent NDDs; 8.8% had multiple disorders.

Conclusions:

  • NDDs are prevalent in children and frequently co-occur with other conditions.
  • Children from low-income backgrounds are more susceptible to NDDs.
  • The study offers critical insights into NDD characteristics and prevalence within a specific Indian population.

Related Concept Videos

Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
50
Autism Spectrum Disorder01:19

Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
75
Intellectual Disability01:29

Intellectual Disability

Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...
44
Conduct Disorder01:28

Conduct Disorder

Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...
30
Oppositional Defiant Disorder01:30

Oppositional Defiant Disorder

A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
23
Specialized Care Centers and Settings-I01:30

Specialized Care Centers and Settings-I

Specialized care settings or centers are situated in convenient locations within the community and offer care to a specific group or population. They consist of daycare facilities, mental health facilities, rural health facilities, educational institutions, industries, shelters for the homeless, and rehabilitation facilities.
Daycare centers
They provide several functions. Some facilities care for healthy newborns and children whose parents work, while others are medically focused and care for...
935