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Plexiform Schwannoma Clinically Masquerading as Thrombosed Vein
D Basnet1, R Makaju1, N Gautam1
1Department of Pathology, Dhulikhel Hospital, Kathmandu University Hospital, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal.
Kathmandu University Medical Journal (KUMJ)
|September 26, 2024
Summary
Plexiform schwannoma, a rare benign nerve tumor, can occur in the lower extremities. This case highlights a large plexiform schwannoma in a young female
Area of Science:
- Oncology
- Pathology
- Dermatology
Background:
- Plexiform schwannoma is a rare, benign nerve sheath tumor typically affecting young adults.
- It commonly presents in the trunk, head, neck, and extremities, usually under 2 cm.
- Distinguishing plexiform schwannoma from plexiform neurofibroma is crucial due to differing recurrence and malignant potential.
Observation:
- A case study of a 14-year-old female with an 11 cm soft tissue mass on her right foot.
- Initial Doppler scan suggested a thrombosed superficial vein.
- Histological evaluation revealed a plexiform schwannoma.
Findings:
- The tumor exhibited a plexiform growth pattern characteristic of schwannoma.
- S-100 immunostaining was diffuse and strong, confirming the diagnosis.
- The large size (11 cm) was atypical for typical plexiform schwannoma presentations.
Implications:
- This case expands the known size spectrum for lower extremity plexiform schwannoma.
- Accurate diagnosis through histology and S-100 staining is vital for appropriate management.
- Highlights the importance of considering rare diagnoses even with initial atypical presentations.
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