Related Experiment Video

Updated: Jun 12, 2025

Electrophysiological Investigations of Retinogeniculate and Corticogeniculate Synapse Function
09:09

Electrophysiological Investigations of Retinogeniculate and Corticogeniculate Synapse Function

Published on: August 7, 2019

6.1K

A perfect recipe for a corticospinal neuron

Alfonso Aguilera1, Marta Nieto1

  • 1Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología (CNB-CSIC) Consejo Superior de Investigaciones Científicas, Madrid, Spain.

Elife
|September 26, 2024
PubMed

Abstract:

A tailored cocktail of genes can reprogram a subset of progenitors to no longer produce glial cells and instead develop into neurons involved in motor control.

Keywords:
corticospinal neuronsglial progenitorsneuroscienceregenerative medicinereprogrammingstem cells

More Related Videos

Bilaminar Co-culture of Primary Rat Cortical Neurons and Glia
12:32

Bilaminar Co-culture of Primary Rat Cortical Neurons and Glia

Published on: November 12, 2011

19.6K
Genetic Manipulation of Cerebellar Granule Neurons In Vitro and In Vivo to Study Neuronal Morphology and Migration
09:07

Genetic Manipulation of Cerebellar Granule Neurons In Vitro and In Vivo to Study Neuronal Morphology and Migration

Published on: March 17, 2014

13.7K

Related Experiment Videos

Last Updated: Jun 12, 2025

Electrophysiological Investigations of Retinogeniculate and Corticogeniculate Synapse Function
09:09

Electrophysiological Investigations of Retinogeniculate and Corticogeniculate Synapse Function

Published on: August 7, 2019

6.1K
Bilaminar Co-culture of Primary Rat Cortical Neurons and Glia
12:32

Bilaminar Co-culture of Primary Rat Cortical Neurons and Glia

Published on: November 12, 2011

19.6K
Genetic Manipulation of Cerebellar Granule Neurons In Vitro and In Vivo to Study Neuronal Morphology and Migration
09:07

Genetic Manipulation of Cerebellar Granule Neurons In Vitro and In Vivo to Study Neuronal Morphology and Migration

Published on: March 17, 2014

13.7K

Related Concept Videos

Neurons: The Cell Body and the Dendrites01:23

Neurons: The Cell Body and the Dendrites

2.8K
A typical nerve cell comprises three main components: the cell body, dendrites, and the axon. The cell body, also known as the soma or perikaryon, serves as the central biosynthetic hub housing a nucleus surrounded by cytoplasm containing organelles commonly found in most cells. Notably, Nissl bodies, clusters of the rough endoplasmic reticulum and free ribosomes responsible for protein synthesis, are distinctive features of the neuronal cell body. As neurons age, aggregates of a brown pigment...
2.8K

Articles linked to this work by shared authors, journal, and citation graph.

Early fate diversification of radial glial progenitors during corticogenesis.

Science advances·2026

A transient sex-biased transcriptional program shapes early postnatal L2/3 neuron development.

Biology of sex differences·2026

Epigenetic regulation of serine biosynthesis by PHF8 during neurogenesis.

EMBO reports·2026

Interhemispheric CA1 projections support spatial cognition and are affected in a mouse model of the 22q11.2 deletion syndrome.

bioRxiv : the preprint server for biology·2024

Early cortical GABAergic interneurons determine the projection patterns of L4 excitatory neurons.

Science advances·2024

CUX1-related neurodevelopmental disorder: deep insights into phenotype-genotype spectrum and underlying pathology.

European journal of human genetics : EJHG·2023

Wound-induced syncytia outpace mononucleate neighbors during Drosophila wound repair.

eLife·2026

PRMT1-SFPQ regulates intron retention to control matrix gene expression during craniofacial development.

eLife·2026

Pathogenic O-GlcNAc dyshomeostasis is associated with cortical malformations and hyperactivity.

eLife·2026

Infants at high and low likelihood for autism show different EEG developmental trajectories in speech tracking and statistical learning.

eLife·2026

MATR3 is essential for oocyte growth and maturation quality through a dual molecular mechanism.

eLife·2026

Enhanced tactile coding in rat neocortex under darkness.

eLife·2026

Neuroprotective Action of Agonists and Modulators of A1 Adenosine Receptors Upon Hyperexcitation: Mechanism of the Antiepileptic Activity and Role of Neuron-Glial Interaction.

Journal of neurochemistry·2026

Anti-Inflammatory Effects of Adipose-Derived Mesenchymal Stem Cells and Their Exosomes in the Cortex and Striatum in a Nonalcoholic Steatohepatitis Model.

Current stem cell research & therapy·2026

Circuit-specific remodeling of synaptic co-transmission in stress-responsive networks.

Animal cells and systems·2026

Harnessing Natural Killer Cells: From Neuroimmunology to Novel Therapies for Central Nervous System Diseases.

MedComm·2026

Neutrophil-Mediated Delivery of MRI-Traceable Nanocarriers Ameliorates Acute Kidney Injury and Associated Cognitive Deficits and Anxiety-Like Behaviors.

Advanced healthcare materials·2026

Complexity and dynamics of partially symmetric random neural networks.

Physical review. E·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us