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Emergent veno-arterial extra-corporeal membrane oxygenator support for refractory acute myocarditis in paediatric

Mimoza Maldi1, Guido M Olivieri2, Simone Ghiselli1

  • 1Congenital Cardiac Surgery De Gasperis Cardio Center, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.

Cardiology in the Young
|September 27, 2024
PubMed

Insights

Severe heart failure in children due to acute myocarditis is rare but serious. Veno-arterial extra-corporeal membrane oxygenation (VA-ECMO) is critical for survival in cardiogenic shock, and this study examines VA-ECMO outcomes.

Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Surgery
  • Critical Care Medicine

Background:

  • Acute myocarditis can cause severe heart failure in children.
  • Refractory cardiogenic shock necessitates mechanical circulatory support.
  • Veno-arterial extra-corporeal membrane oxygenation (VA-ECMO) is a key intervention.

Purpose of the Study:

  • To evaluate short- and long-term patient outcomes.
  • To analyze the effectiveness of VA-ECMO in pediatric acute myocarditis.
  • To provide data on survival and recovery post-VA-ECMO.

Main Methods:

  • Retrospective analysis of pediatric patients with acute myocarditis.
  • Inclusion of patients requiring VA-ECMO for cardiogenic shock.
  • Assessment of in-hospital, short-term, and long-term outcomes.

Main Results:

  • In-hospital mortality for VA-ECMO support is approximately 30%.
  • VA-ECMO effectively restores perfusion in pediatric cardiogenic shock.
  • Further analysis of short- and long-term outcomes is presented.

Conclusions:

  • VA-ECMO is a vital treatment for pediatric acute myocarditis with refractory cardiogenic shock.
  • Understanding VA-ECMO outcomes is crucial for patient management.
  • This study contributes to the knowledge of VA-ECMO's role in pediatric critical care.

Keywords:
Extra-corporeal membrane oxygenationacute myocarditisheart failurepaediatric cardiogenic shockrefractory cardiogenic shock

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