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The azygos system is a crucial part of the body's circulatory system and drains most of the thorax. It comprises the azygos, hemiazygos, and accessory hemiazygos veins.
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The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
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Systemic veins are crucial blood vessels that return deoxygenated blood from various body tissues back to the heart. There are three systemic veins that return deoxygenated blood to the heart, they are as follows.
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The human body is a complex system of interconnected parts, and the circulatory system plays a crucial role in maintaining overall health. One key component of this system is the inferior vena cava, a large vein responsible for returning blood from the abdominopelvic viscera and abdominal walls to the heart.
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Updated: Jun 12, 2025

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
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Persistent Left-Sided Superior Vena Cava: A Case Report.

Matthew Hentges1, Karson Schroeder1, Aleesha Somani1

  • 1General Surgery, Kansas City University, Kansas City, USA.

Cureus
|September 27, 2024
PubMed
Summary

A persistent left-sided superior vena cava (PLSVC) is a rare thoracic venous anomaly. This case report details an incidental finding of isolated PLSVC in a 48-year-old male, discussing its origins and clinical significance.

Keywords:
anatomy and physiologycentral line insertiongeneral and vascular surgerypersistent left-sided superior vena cava (plsvc)ultrasound-guided

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Area of Science:

  • Cardiovascular Anatomy
  • Embryology
  • Radiology

Background:

  • Persistent left-sided superior vena cava (PLSVC) is the most common thoracic venous anomaly, though rare overall.
  • It arises from abnormal embryological development where the left anterior cardinal vein fails to regress.
  • Often associated with congenital heart disease, PLSVC can present with isolated or duplicated SVCs.

Observation:

  • A case report of a 48-year-old male incidentally found to have an isolated PLSVC.
  • The anomaly was identified on a chest X-ray following the placement of a temporary dialysis catheter.
  • This highlights the potential for incidental detection in routine imaging.

Findings:

  • Detailed description of the embryological origin of PLSVC, including anatomical variants.
  • Discussion of the incidence and prevalence of this rare venous anomaly.
  • Analysis of the clinical significance and potential implications of PLSVC.

Implications:

  • PLSVC, while rare, has clinical significance and can be incidentally discovered.
  • Understanding its embryological basis and anatomical variations is crucial for diagnosis.
  • Awareness aids in appropriate patient management and interpretation of thoracic imaging.