Related Experiment Video
Updated: Jun 12, 2025

Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons
Published on: January 7, 2019
A Case of Charcot-Marie-Tooth Disease Causing Colitis and Electrolyte Imbalances
Stefany Panunzio1, Lester Couch1, Asm Rahman2
1Department of Research, Alabama College of Osteopathic Medicine, Dothan, USA.
Abstract:
Peripheral nerve injury is a result of the rare and crippling Charcot-Marie-Tooth (CMT) disease. Although it can happen at any age, progressive muscle weakening is most obvious in adolescence or the early stages of adulthood. We present a case of an 81-year-old female with recurrent urinary tract infections (UTIs), complaints of abdominal pain and constipation, as well as dysuria with abnormal electrolyte levels. This case serves as an effective symptomatic treatment plan for a patient with this rare neuromuscular disorder.
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