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Updated: Jun 12, 2025

Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
Published on: May 16, 2014
Recent advances in the synthesis of highly substituted imidazolidines
Abolfazl Olyaei1, Mahdieh Sadeghpour2
1Department of Chemistry, Faculty of Science, Imam Khomeini International University Qazvin Iran olyaei_a@sci.ikiu.ac.ir.
Abstract:
Imidazolidine is a saturated heterocycle with a cyclic aminal core that can be found in natural products and biologically active molecules. Additionally, these heterocyclic compounds have been utilized as chiral ligands, N-heterocyclic carbene precursors, and catalysts in organic synthesis. This review is an attempt to compile the literature of various synthetic procedures of highly substituted imidazolidines, chiral imidazolidines with high diastereoselectivities and enantioselectivities, bis-imidazolidines, and spiro-imidazolidines, as well as their pharmacological properties during the period from 1949 to 2023.
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