Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

222
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
222
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

228
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
228
Clot Retraction and Fibrinolysis01:16

Clot Retraction and Fibrinolysis

8.1K
After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.
8.1K
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

1.5K
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
1.5K
Flail Chest-II01:26

Flail Chest-II

453
Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
453
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants01:18

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants

1.9K
Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The role of reduced red cell deformability in the pathogenesis of severe falciparum malaria and its restoration by blood transfusion.

Transactions of the Royal Society of Tropical Medicine and Hygiene·2002
Same author

The resistance to physiological shear stresses of the erythrocytic rosettes formed by cells infected with Plasmodium falciparum.

Annals of tropical medicine and parasitology·2000
Same author

Abnormal blood flow and red blood cell deformability in severe malaria.

Parasitology today (Personal ed.)·2000
Same author

Red blood cell deformability as a predictor of anemia in severe falciparum malaria.

The American journal of tropical medicine and hygiene·1999
Same author

Red cell deformability, splenic function and anaemia in thalassaemia.

British journal of haematology·1999
Same author

Red blood cell rigidification during cyclosporin therapy: a possible early warning signal for adverse reactions.

Scandinavian journal of clinical and laboratory investigation·1999

Related Experiment Video

Updated: Dec 29, 2025

Author Spotlight: Advancing Thrombolytic Testing by Integrating Flow Dynamics in In Vitro Models
06:16

Author Spotlight: Advancing Thrombolytic Testing by Integrating Flow Dynamics in In Vitro Models

Published on: April 19, 2024

1.6K

[Fibrinolytic therapy]

J Vreeken

    Nederlands Tijdschrift Voor Geneeskunde
    |September 7, 1985
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Author Spotlight: A Novel Method for Comprehensive Cell Component Analysis of Cerebral Blood Clots
    06:12

    Author Spotlight: A Novel Method for Comprehensive Cell Component Analysis of Cerebral Blood Clots

    Published on: July 21, 2023

    926
    An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug
    07:50

    An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug

    Published on: June 4, 2021

    3.1K

    Related Experiment Videos

    Last Updated: Dec 29, 2025

    Author Spotlight: Advancing Thrombolytic Testing by Integrating Flow Dynamics in In Vitro Models
    06:16

    Author Spotlight: Advancing Thrombolytic Testing by Integrating Flow Dynamics in In Vitro Models

    Published on: April 19, 2024

    1.6K
    Author Spotlight: A Novel Method for Comprehensive Cell Component Analysis of Cerebral Blood Clots
    06:12

    Author Spotlight: A Novel Method for Comprehensive Cell Component Analysis of Cerebral Blood Clots

    Published on: July 21, 2023

    926
    An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug
    07:50

    An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug

    Published on: June 4, 2021

    3.1K