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Published on: April 3, 2016
Effectiveness of Defocus Incorporated Multiple Segments in Slowing Myopia Progression in Pediatric Patients as a
Luca Buzzonetti1, Sergio Petroni1, Matteo Federici1
1Ophthalmology Unit, Bambino Gesù IRCCS Children's Hospital, Via Torre di Palidoro snc, Passoscuro, 00050 Rome, Italy.
Abstract:
Background: The purpose of this study is to evaluate the effectiveness of Defocus Incorporated Multiple Segments (DIMSs) in slowing myopia progression in pediatric patients as a function of age. Methods: This was a non-randomized experimenter-masked retrospective controlled observational study of European individuals aged 6-16 years with progressive myopia but no ocular pathology. We retrospectively reviewed the charts of the participants allocated to receive DIMS spectacles (Hoya® MiyoSmart®) or single-vision spectacle lenses (control group). Cycloplegic spherical equivalent (SE) and axial length (AL) were measured at baseline and at 12-, 24-, and 36-month follow-ups. The results were stratified by age into four groups: patients wearing DIMS spectacles older or younger than 10 years of age (group A, 20 patients mean age 13.6 ± 2.2, and group C, 20 patients mean age 9.0 ± 1.2) and age-matched control groups (group B, 18 patients mean age 13.2 ± 2.5, and group D, 22 patients mean age 8.5 ± 0.9). Results: At 36 months, SE and AL increase were significantly reduced in groups A and C, respectively, compared to groups B and D (p < 0.05). Linear regression analysis showed a significant correlation (p < 0.05) between patient age and myopia progression for SE in groups A and C, but only in group A for AL. Groups B and D did not show any significant correlation (p > 0.05). Conclusions: DIMS spectacles seem to slow myopia progression in pediatric patients; however, their effectiveness shows the greatest results in children older than 10 years of age. Moreover, our findings suggest that AL may be the more reliable parameter for evaluating myopia progression.
Insights
Defocus Incorporated Multiple Segments (DIMS) spectacles effectively slow myopia progression in children. The study found DIMS lenses were most effective in slowing myopia in pediatric patients older than 10 years.
Area of Science:
- Ophthalmology
- Pediatric Optometry
- Myopia Control Research
Background:
- Progressive myopia in children is a growing concern.
- Defocus Incorporated Multiple Segments (DIMS) spectacles offer a potential solution for myopia control.
- Understanding the age-dependent effectiveness of DIMS is crucial for clinical application.
Purpose of the Study:
- To evaluate the efficacy of DIMS spectacles in mitigating myopia progression in pediatric patients.
- To analyze the influence of patient age on the effectiveness of DIMS for myopia control.
- To compare DIMS efficacy against single-vision lenses in a controlled observational study.
Main Methods:
- A retrospective, non-randomized, masked observational study was conducted on European children aged 6-16 years with progressive myopia.
- Participants were assigned to either DIMS spectacles (Hoya MiyoSmart) or standard single-vision lenses (control).
- Cycloplegic spherical equivalent (SE) and axial length (AL) were measured at baseline and 36-month follow-up, with data stratified by age groups.
Main Results:
- DIMS spectacles significantly reduced SE and AL progression over 36 months compared to controls (p < 0.05).
- A significant correlation between age and myopia progression was observed for SE in DIMS groups and AL in the older DIMS group.
- No significant correlation between age and myopia progression was found in the control groups.
Conclusions:
- DIMS spectacles demonstrate effectiveness in slowing myopia progression in pediatric populations.
- The study highlights that DIMS lenses yield superior results in children over 10 years of age.
- Axial length (AL) appears to be a more reliable indicator for monitoring myopia progression than SE.
