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Cancer and Heart Failure: Dangerous Liaisons
Davide Bertolini1,2, Carmine Pizzi1,2, Erwan Donal3
1Cardiology Unit, Cardiac Thoracic and Vascular Department, IRCCS Azienda Ospedaliera-Universitaria di Bologna, 40138 Bologna, Italy.
Journal of Cardiovascular Development and Disease
|September 27, 2024
Summary
Cancer and heart failure (HF) are growing global concerns. This review explores their link, focusing on cancer treatment risks to the heart and managing heart failure during cancer therapy.
Area of Science:
- Oncology and Cardiology
- Cardio-oncology
Background:
- Cancer and heart failure (HF) present significant global health challenges.
- The interplay between cancer and HF is increasingly recognized in epidemiology and clinical practice.
Purpose of the Study:
- To explore the relationship between cancer and HF.
- To identify risk factors and cardiotoxic effects of chemotherapy.
- To review the diagnosis and management of cancer therapy-related HF.
Main Methods:
- Literature review of existing evidence.
- Analysis of risk factors for cancer and HF.
- Examination of cardiotoxicity from chemotherapy agents.
- Synthesis of current diagnostic and management strategies for HF in cancer patients.
Main Results:
- Chemotherapy agents can induce cardiotoxicity, increasing HF risk.
- Early diagnosis and tailored management are crucial for HF in cancer patients.
- Significant gaps in knowledge and future research directions were identified.
Conclusions:
- The relationship between cancer and HF necessitates a multidisciplinary approach.
- Understanding cardiotoxicity and optimizing HF management are key to improving patient outcomes.
- Further research is needed to address knowledge gaps in cardio-oncology.
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