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Anticoagulation Patterns in Ischemic Stroke Patients with Atrial Fibrillation in Developing Country: Insights from

Mai Duy Ton1,2,3, Dao Viet Phuong1,2,3, Nguyen Tien Dung1,2,3

  • 1Stroke Center, Bach Mai Hospital, Hanoi 100000, Vietnam.

Journal of Cardiovascular Development and Disease
|September 27, 2024
PubMed

Insights

Atrial fibrillation (AF) significantly worsens outcomes for ischemic stroke and TIA patients in Vietnam. While oral anticoagulation (OAC) use increased by discharge, improved AF management is crucial for stroke prevention.

Area of Science:

  • Cardiology
  • Neurology
  • Public Health

Background:

  • Atrial fibrillation (AF) presents a growing global cardiovascular challenge, particularly in Vietnam.
  • Understanding AF's impact on ischemic stroke/transient ischemic attack (TIA) and treatment patterns is critical.

Purpose of the Study:

  • To investigate the influence of AF on ischemic stroke/TIA outcomes in Vietnam.
  • To assess the utilization of oral anticoagulation (OAC) therapy among these patients.

Main Methods:

  • Utilized data from the Registry of Stroke Care Quality (RES-Q) in 66 Vietnamese hospitals (2017-2023).
  • Included patients diagnosed with ischemic stroke or TIA, analyzing clinical characteristics, medication use, and outcomes.

Main Results:

  • 15.1% of 94,144 patients had AF; these patients were older with more comorbidities and severe strokes.
  • AF was linked to higher in-hospital mortality and poorer prognosis.
  • OAC utilization rose from 15.8% pre-hospitalization to 82.4% at discharge, favoring direct oral anticoagulants.

Conclusions:

  • AF significantly impacts ischemic stroke/TIA outcomes in Vietnam.
  • While OAC use improved during hospitalization, pre-hospitalization rates were low, highlighting a need for better AF management and stroke prevention strategies in developing nations.

Keywords:
RES-QVietnamatrial fibrillationischemic strokeoral anticoagulationstroke prevention

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