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Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs
Published on: July 23, 2016
Occlusive retinal vasculitis associated with intravitreal Faricimab injections
Felix F Reichel1,2, Peter Kiraly3, Roopa Vemala3
1Centre for Ophthalmology, University Eye Hospital, University Hospital Tübingen, Tübingen, Germany. felix.reichel@ouh.nhs.uk.
Purpose:
We describe a case of occlusive vasculitis associated with intravitreal Faricimab (Vabysmo) injections.
Methods:
A retrospective case report.
Results:
A 52-year old man treated with monthly Faricimab injections for diabetic macula oedema presented with sudden reduced vision, new retinal hemorrhages, significant retinal vascular occlusions and ischemia. After screening for differential diagnoses was unremarkable, the patient was treated with oral and intravitreal steroid therapy under which the occlusive vasculitis was stabilized.
Conclusion:
Occlusive vasculitis, though rare, is a potential complication of Faricimab therapy. Comprehensive reporting and large-scale analyses are essential to better understand and manage this adverse event.

