A Self-Powered Enzymatic Glucose Sensor Utilizing Bimetallic Nanoparticle Composites Modified Pencil Graphite...

Area of Science:

• Electrochemistry
• Biosensors
• Green Energy

Background:

• Enzymatic biofuel cells (EBFCs) offer sustainable energy solutions using biofuels and biocatalysts.
• Developing efficient and stable electrode materials is crucial for EBFC performance.

Purpose of the Study:

• To design and characterize a novel EBFC for simultaneous glucose detection and power generation.
• To develop a composite anode and a bimetallic nanoparticle cathode for enhanced performance.

Main Methods:

• Fabrication of a glassy carbon electrode (GCE) anode modified with multi-walled carbon nanotubes (MWCNT), ferrocene (Fc), and glucose oxidase (GOx).
• Modification of a pencil graphite electrode (PGE) cathode with platinum-palladium bimetallic nanoparticles (Pt-PdNps).
• Electrochemical characterization using chronoamperometry (CA) and optimization of the EBFC.

Main Results:

• The MWCNT-Fc-GOx/GCE anode showed a linear response to glucose (1-10 mM) with a limit of detection (LOD) of 0.26 mM.
• The EBFC achieved an open circuit potential of 285.0 mV and a maximum power density of 32.25 µW cm⁻².
• The sensor exhibited good selectivity, with minimal interference from common biological molecules except ascorbic acid, uric acid, and dopamine.

Conclusions:

• The developed EBFC, featuring an enzymatic composite anode and a bimetallic nanozyme cathode, is a promising system for glucose sensing.
• This design offers a dual function of detecting glucose and harvesting energy from glucose-containing fluids.
• The study highlights the potential of advanced nanomaterials and enzyme immobilization for creating efficient biosensing platforms.