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Liquid Atmospheric Pressure Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Using a Commercial Ion

Bob Challen1, Lily R Adair1, Rainer Cramer1

  • 1Department of Chemistry, University of Reading, Whiteknights, Reading, RG6 6DX, U.K.

Analytical Chemistry
|September 27, 2024
PubMed
Summary

A new liquid atmospheric pressure-matrix-assisted laser desorption/ionization (LAP-MALDI) method enables electrospray ionization-like mass spectra acquisition using commercial mass spectrometry equipment. This technique enhances bacterial proteoform and species identification with high resolution and mass accuracy.

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