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Updated: Jun 11, 2025

A Two-Step Method for Percutaneous Transhepatic Choledochoscopic Lithotomy
Published on: September 13, 2022
Successful application of percutaneous endoscopic cholangioscopy + electrohydraulic lithotripsy for hepatolithiasis
Ana Clarete1, Daniela Nasner2, Juan Sebastián Toro-Gutiérrez3
1Clinical Research Center, Fundación Valle del Lili, Cali, Colombia. ana.clarete@fvl.org.co.
Insights
Percutaneous cholangioscopy with electrohydraulic lithotripsy effectively removed intrahepatic gallstones in a pediatric liver transplant patient, offering a non-surgical solution for this rare complication.
Area of Science:
- Hepatology
- Pediatric Gastroenterology
- Interventional Radiology
Background:
- Liver transplantation is vital for pediatric end-stage liver disease.
- Biliary stones are a rare but challenging complication post-pediatric liver transplant.
- Endoscopic treatments are often not feasible in pediatric post-transplant biliary stone cases.
Observation:
- A 7-year-old pediatric liver transplant recipient developed recurrent cholangitis 4 months post-transplant.
- Cholangioresonance identified intrahepatic lithiasis and anastomotic stenosis.
- Initial percutaneous cholangiography failed to remove immobile, peripheral gallstones.
Findings:
- Percutaneous endoscopic cholangioscopy with the SpyGlass Discover system enabled direct visualization of bile ducts.
- Electrohydraulic lithotripsy successfully fragmented and removed intrahepatic stones.
- The procedure was performed without complications in the pediatric patient.
Implications:
- Percutaneous cholangioscopy with intraductal lithotripsy is a viable, non-surgical option for pediatric post-transplant biliary stones.
- This technique allows for accurate stone identification and extraction.
- Further research is needed on this approach in the pediatric population due to limited literature.
Background:
Liver transplantation in pediatric patients is a crucial intervention for treating end-stage hepatic diseases. Despite significant advances in surgical techniques and postoperative care, complications remain a substantial challenge in this population. Biliary stones, an infrequent complication, present challenges in this context. Given the impossibility of endoscopic treatments, different strategies have been explored to address post-liver transplantation gallstones in children by implementing percutaneous treatment with intraductal lithotripsy.
Case Presentation:
A 7-year-old Latin patient, who had a diagnosis of biliary atresia at the age of 2, underwent a liver transplant from a living donor. However, 4 months after the transplant, the patient experienced recurring episodes of cholangitis. Cholangioresonance revealed intrahepatic lithiasis and anastomotic stenosis. Attempted gallstone removal through percutaneous cholangiography proved unsuccessful, as multiple peripheral stones in all ducts remained immobile. Subsequently, a percutaneous endoscopic cholangioscopy using the SpyGlass Discover system for visual examination of the bile ducts + electrohydraulic lithotripsy was performed, effectively removing the stones without any complications.
Conclusions:
Percutaneous cholangioscopy with intraductal lithotripsy enables accurate identification and extraction of intrahepatic stones without the need for surgical intervention. This method proves to be a valuable alternative in addressing post-transplant biliary stone. In our case, it was performed on a pediatric patient who underwent liver transplantation, which makes it interesting and relevant as there is currently insufficient literature on this approach in such cases in this population.
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