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Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
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Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

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Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
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Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

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Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

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Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
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Disorders of Hemostasis01:24

Disorders of Hemostasis

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Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
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Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

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A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
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Related Experiment Video

Updated: Jun 11, 2025

Author Spotlight: Advancing Cancer Associated Thrombosis Research in Rodent Models
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Thrombotic Complications in Pediatric Cancer.

Alkistis Adramerina1, Marina Economou1

  • 11st Pediatric Department, Faculty of Health Sciences, School of Medicine, Aristotle University of Thessaloniki, 54250 Thessaloniki, Greece.

Children (Basel, Switzerland)
|September 28, 2024
PubMed
Summary

Pediatric cancer patients frequently experience thromboembolism (TE), influenced by cancer type, treatment, and genetic factors. Further research is needed for effective prevention and management strategies in children with cancer.

Keywords:
anticoagulantspediatric cancerthromboembolismthrombophilia

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Area of Science:

  • Oncology
  • Hematology
  • Pediatrics

Background:

  • Thromboembolism (TE) is a significant complication in pediatric cancer patients.
  • Risk factors include age, blood group, cancer type/site, inherited thrombophilia, central venous catheter, and chemotherapy.

Purpose of the Study:

  • To review the current understanding of cancer-related TE in children.
  • To highlight the need for evidence-based guidelines and further research.

Main Methods:

  • Literature review of risk factors, management, and prevention of TE in pediatric oncology.
  • Analysis of current treatment limitations and potential alternatives.

Main Results:

  • TE commonly affects extremities in pediatric cancer patients.
  • Current management relies on general pediatric TE guidelines due to lack of specific pediatric oncology protocols.
  • Direct oral anticoagulants show potential but require further safety and efficacy studies in this population.

Conclusions:

  • Cancer-related TE remains a significant cause of morbidity in pediatric oncology.
  • There is a critical need for large multicenter trials to establish guidelines for TE management and thromboprophylaxis in children with cancer.