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NoxO1 Determines the Level of ROS Formation by the Nox1-Centered NADPH Oxidase

Dana Maureen Hebchen1, Manuela Spaeth1, Niklas Müller1

  • 1Institute for Cardiovascular Physiology, Goethe University Frankfurt, 60298 Frankfurt, Germany.

Antioxidants (Basel, Switzerland)
|September 28, 2024
PubMed
Summary

Reactive oxygen species (ROS) formation by the Nox1-centered NADPH oxidase complex is regulated by the cytosolic subunit NoxO1. This study demonstrates that increased NoxO1 concentration controls ROS production in a dose-dependent manner.

Keywords:
Nox1NoxA1NoxO1reactive oxygen species

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