Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

1
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
1
Imaging Studies II: Ultrasonography01:24

Imaging Studies II: Ultrasonography

1
IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
1
Imaging Studies I: Kidney, Ureter, and Bladder Studies01:28

Imaging Studies I: Kidney, Ureter, and Bladder Studies

1
Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
1
Imaging Studies VI: Voiding Cystourethrography and Cystography01:22

Imaging Studies VI: Voiding Cystourethrography and Cystography

1
Voiding Cystourethrography (VCUG) and Cystography are specialized radiographic procedures used to examine the structure and function of the bladder and urethra.Voiding Cystourethrography (VCUG)A Voiding Cystourethrogram (VCUG) is a diagnostic imaging procedure that assesses the anatomy and function of the lower urinary tract. It focuses on the bladder, bladder neck, and urethra, helping detect abnormalities such as vesicoureteral reflux (VUR)—the backward or reverse flow of urine into the...
1
  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Oncology And Carcinogenesis
  9. Predictive And Prognostic Markers
  11. Radiomics-based Computed Tomography Urogram Approach For The Prediction Of Survival And Recurrence In Upper Urinary Tract Urothelial Carcinoma

Radiomics-Based Computed Tomography Urogram Approach for the Prediction of Survival and Recurrence in Upper Urinary Tract Urothelial Carcinoma

Abdulsalam Alqahtani1,2, Sourav Bhattacharjee3, Abdulrahman Almopti1

  • 1School of Medicine, Centre for Medical Engineering and Technology, University of Dundee, Dundee DD1 9SY, UK.

Cancers
|September 28, 2024

Related Experiment Videos

Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors
05:19

Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors

Published on: March 29, 2019

10.3K
Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis
09:28

Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis

Published on: May 12, 2019

10.1K
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
09:31

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

Published on: March 30, 2015

8.8K

View abstract on PubMed

Summary
This summary is machine-generated.

Accurate prediction of survival and recurrence in upper tract urothelial carcinoma (UTUC) is improved by combining radiomics and clinical data from CT urograms. This approach enhances prognostic performance for better patient risk stratification.

Area of Science:

  • Oncology
  • Radiology
  • Medical Imaging

Background:

  • Upper tract urothelial carcinoma (UTUC) is an aggressive cancer with a poor prognosis.
  • Accurate prediction of survival and recurrence is vital for risk stratification and treatment decisions in UTUC patients.

Purpose of the Study:

  • To develop and validate a model combining radiomics and clinicopathological features for predicting survival and recurrence in UTUC.
  • To assess the prognostic performance of CT-urogram-derived radiomics features in UTUC.

Main Methods:

  • Analysis of preoperative CT urograms and clinical data from 106 UTUC patients.
  • Extraction of radiomics features and selection using the LASSO method.
  • Development of multivariable Cox models integrating radiomics and clinical factors.
Keywords:
CT urogramUTUCprognosisradiomics

Related Experiment Videos

Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors
05:19

Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors

Published on: March 29, 2019

10.3K
Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis
09:28

Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis

Published on: May 12, 2019

10.1K
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
09:31

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses

Published on: March 30, 2015

8.8K

Main Results:

  • The combined radiomics and clinical model demonstrated superior predictive accuracy for survival (C-index: 0.73) and recurrence (C-index: 0.84).
  • Kaplan-Meier analysis revealed significant differences in survival (p < 0.0001) and recurrence (p < 0.002) probabilities.
  • Multivariable Cox models identified significant predictors for UTUC outcomes.

Conclusions:

  • CT-urogram-based radiomics models effectively predict survival and recurrence in UTUC.
  • Combining radiomics features with clinical factors significantly enhances prognostic performance for UTUC.
recurrence
survival
texture analysis