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Updated: May 10, 2026

A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology
Published on: May 6, 2014
Editorial to the Special Issue "Molecular and Cellular Mechanisms of CVD: Focus on Atherosclerosis"
Nikita G Nikiforov1,2,3
1Laboratory of Angiopathology, The Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia.
Insights
This special issue explores molecular and cellular mechanisms driving atherosclerosis, a key process in cardiovascular disease (CVD). Understanding these pathways is crucial for developing targeted therapies against CVD.
Area of Science:
- Cardiovascular Science
- Molecular Biology
- Cellular Biology
Background:
- Atherosclerosis is a complex cardiovascular disease (CVD) process.
- Understanding its molecular and cellular underpinnings is critical for effective treatment.
Discussion:
- This special issue focuses on the intricate molecular and cellular mechanisms driving atherogenesis.
- It highlights key pathways involved in the development and progression of atherosclerosis.
Key Insights:
- Exploration of novel molecular targets in atherosclerosis.
- Insights into cellular responses contributing to plaque formation.
- Advancements in understanding the cellular and molecular basis of CVD.
Outlook:
- Future research directions in atherogenesis.
- Potential for new therapeutic strategies targeting molecular and cellular mechanisms.
- Advancing the fight against cardiovascular disease through deeper mechanistic understanding.
Abstract:
The current Special Issue, "Molecular and Cellular Mechanisms of CVD: Focus on Atherosclerosis", is dedicated to exploring the various mechanisms involved in atherogenesis [...].
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