Long-Term Results and Quality of Life after Surgery for Acute Aortic Dissection Type A: Contemporary Single-Centre

Nora Goebel1, Simone A Holder1, Franziska Huether1

  • 1Department of Cardiovascular Surgery, Robert Bosch Hospital, 70376 Stuttgart, Germany.

Journal of Clinical Medicine
|September 28, 2024
PubMed

Insights

Emergency surgery for acute aortic dissection type A shows improved 30-day and 10-year survival rates over time, despite increased patient complexity. Quality of life remains significantly impaired post-surgery.

Area of Science:

  • Cardiovascular Surgery
  • Thoracic Surgery
  • Aortic Disease Management

Background:

  • Acute aortic dissection type A carries high morbidity and mortality.
  • Emergency surgical intervention is critical for survival.
  • Long-term outcomes and quality of life post-surgery require ongoing evaluation.

Purpose of the Study:

  • To assess long-term outcomes and quality of life after emergency surgery for acute aortic dissection type A.
  • To compare early versus late surgical periods regarding mortality and reoperation rates.
  • To analyze risk factors influencing outcomes in aortic dissection surgery.

Main Methods:

  • Retrospective analysis of 413 patients undergoing surgery for acute aortic dissection type A between 2000 and 2016.
  • Comparison of outcomes between two periods: 2000-2007 (early) and 2008-2016 (late).
  • Assessment of 30-day mortality, follow-up mortality, reoperation rates, and quality of life using the SF-36 survey.

Main Results:

  • Perioperative risk (Euroscore) significantly increased from 24.9% to 38.0% (p < 0.001).
  • Thirty-day mortality significantly decreased from 26.7% to 17.4% (p = 0.03).
  • Ten-year survival improved from 53.4% to 69.7% (p = 0.04), with comparable reoperation rates (74.0% vs. 85.7%, p = 0.28).

Conclusions:

  • Surgical outcomes for type A aortic dissection have significantly improved over time, evidenced by reduced 30-day and enhanced 10-year survival.
  • Despite improvements, quality of life remains significantly impaired compared to the general population.
  • Increased surgical complexity and patient risk are associated with improved, rather than worsened, outcomes in recent years.

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