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Association of Diagonal Earlobe Crease with Risk of Atrial Fibrillation in Stable Patients with Coronary Artery

Moo-Nyun Jin1, Changho Song2, Young Ju Kim3

  • 1Division of Cardiology, Ewha Womans University Medical Center, Ewha Womans University College of Medicine, Seoul 07985, Republic of Korea.

Journal of Clinical Medicine
|September 28, 2024
PubMed

Insights

A diagonal earlobe crease (DELC) may indicate a higher risk of developing atrial fibrillation (AF) in patients with coronary artery disease (CAD). This finding could help identify individuals with CAD who are more prone to AF.

Area of Science:

  • Cardiology
  • Clinical Research
  • Predictive Markers

Background:

  • Diagonal earlobe crease (DELC) is a potential indicator for coronary artery disease (CAD).
  • Limited research exists on the link between DELC and atrial fibrillation (AF).

Purpose of the Study:

  • To investigate the association between DELC and the incidence of AF in patients diagnosed with CAD.

Main Methods:

  • 669 CAD patients under 65 without AF were assessed for DELC.
  • Follow-up was conducted for a median of 44.6 months to record AF incidence.
  • Kaplan-Meier analysis and adjusted hazard ratios were used to evaluate risk.

Main Results:

  • DELC was present in 10.8% of the study cohort.
  • AF incidence was 16.4% in the DELC group versus 8.4% in the non-DELC group.
  • DELC was significantly associated with a higher risk of AF development (aHR=1.88).

Conclusions:

  • DELC is linked to an increased risk of AF in patients with CAD.
  • This visible marker may assist in early AF detection among CAD patients.

Keywords:
atrial fibrillationcoronary artery diseasediagonal earlobe crease

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