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Bilateral Total Knee Arthroplasty (TKA) in a One-Stage Procedure Versus Two-Stage Procedure: A Retrospective Study
Giada Accatino1, Alessandra Monzio Compagnoni1, Federico Alberto Grassi1,2
1Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University Study of Pavia, 27100 Pavia, Italy.
Healthcare (Basel, Switzerland)
|September 28, 2024
Summary
Simultaneous bilateral total knee arthroplasty (TKA) offers a safe alternative to staged procedures for knee arthritis, showing comparable complication rates and improved functional outcomes. This one-stage approach may reduce patient stress and healthcare costs.
Area of Science:
- Orthopedics
- Reconstructive Surgery
Background:
- Osteoarthritis is a leading cause of knee joint replacement globally.
- Bilateral knee arthritis necessitates treatment options balancing efficacy and patient burden.
Purpose of the Study:
- To compare the safety and functional outcomes of simultaneous bilateral total knee arthroplasty (TKA) versus two-stage bilateral TKA.
- To determine if the one-stage TKA approach is non-inferior to the two-stage method regarding complications and recovery.
Main Methods:
- Retrospective analysis of two cohorts: 43 patients undergoing one-stage bilateral TKA and 66 patients receiving two-stage TKA.
- Data collection included demographics, comorbidities, complications, and functional outcomes (Oxford Knee Score, EQ-5L, VAS) at pre-operative and 5-year follow-ups.
Main Results:
- Both groups showed significant quality-of-life improvements, with the one-stage group demonstrating greater enhancement in Oxford Knee Score (p < 0.05).
- Complication rates, including infections, were similar between the one-stage and two-stage bilateral TKA procedures.
Conclusions:
- One-stage bilateral TKA is a safe alternative for selected patients with bilateral knee arthritis, potentially reducing patient stress and healthcare expenses.
- Patient selection based on overall health status is crucial for optimizing surgical outcomes.
- Further large-scale studies are recommended to validate these findings.

