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Related Experiment Video

Updated: Jun 11, 2025

Glass-Based Devices to Generate Drops and Emulsions

Glass-Based Devices to Generate Drops and Emulsions

Published on: April 5, 2022

A Novel Device for Micro-Droplets Generation Based on the Stepwise Membrane Emulsification Principle.

Lei Lei^1,2, Sven Achenbach³, Garth Wells⁴

¹School of Integrated Circuit Science and Engineering, Beihang University, Beijing 100191, China.

|September 28, 2024

Summary

A novel stepwise membrane emulsification device achieves 2.3 μm microspheres, a significant improvement over traditional methods. This cost-effective design offers high-performance droplet production for industrial applications.

Keywords:

SU-8 membrane emulsification process microspheres generation photolithography stepwise structure

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Last Updated: Jun 11, 2025

Glass-Based Devices to Generate Drops and Emulsions

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Published on: April 5, 2022

Fabricating High-viscosity Droplets using Microfluidic Capillary Device with Phase-inversion Co-flow Structure

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Published on: April 17, 2018

Double Emulsion Generation Using a Polydimethylsiloxane PDMS Co-axial Flow Focus Device

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Published on: December 25, 2015

Area of Science:

Materials Science and Engineering
Microfluidics and Nanotechnology

Background:

Traditional membrane emulsification methods typically produce microspheres around 20 μm.
Achieving smaller, uniform microspheres is crucial for various industrial applications.
Existing methods often involve high-cost materials or complex fabrication processes.

Purpose of the Study:

To introduce a novel device for microsphere generation using membrane emulsification.
To present a new stepwise membrane structure for enhanced droplet production.
To demonstrate a cost-effective fabrication method for the proposed membrane.

Main Methods:

Design and fabrication of a novel two-layer or stepwise membrane structure.
Utilized low-cost SU-8 material and conventional lithography with image-based alignment.
Experimental validation of the membrane's performance in microsphere generation.

Main Results:

Successfully generated microspheres with a mean size of 2.3 μm.
Achieved high size uniformity with a standard deviation of 0.8 μm.
Demonstrated significant improvement compared to traditional methods producing 20 μm microspheres.

Conclusions:

The proposed stepwise membrane design principle enables high-performance microsphere production.
Cost-effective fabrication using SU-8 and conventional lithography is feasible.
The developed device meets industrial requirements for precise microsphere generation.