Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Surface Membrane Barriers01:18

Surface Membrane Barriers

1.1K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.1K
Antimicrobial Proteins01:23

Antimicrobial Proteins

945
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
945
Hand hygiene01:23

Hand hygiene

3.1K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
3.1K
Combined Effects of Drugs: Synergism01:27

Combined Effects of Drugs: Synergism

3.8K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
3.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Plant-Derived Terpenes as Emerging Therapeutics Against Schistosomiasis.

International journal of molecular sciences·2026
Same author

Valorization of Olive Stones: Chemical Composition and Bioactivity.

Pharmaceuticals (Basel, Switzerland)·2026
Same author

Chromatography and Mass Spectrometry: Evolving Techniques for Food Analysis.

Foods (Basel, Switzerland)·2025
Same author

Triterpenes Drug Delivery Systems, a Modern Approach for Arthritis Targeted Therapy.

Pharmaceuticals (Basel, Switzerland)·2024
Same author

Myrsinane-Type Diterpenes: A Comprehensive Review on Structural Diversity, Chemistry and Biological Activities.

International journal of molecular sciences·2024
Same author

Placebo-Controlled Trial of Daily Oral Cannabidiol as Adjunctive Treatment for Cats with Chronic Gingivostomatitis.

Animals : an open access journal from MDPI·2023

Related Experiment Video

Updated: Jun 11, 2025

Enhanced Oil Recovery using a Combination of Biosurfactants
13:19

Enhanced Oil Recovery using a Combination of Biosurfactants

Published on: June 3, 2022

5.1K

Exploring Biosurfactants as Antimicrobial Approaches.

Madalena Lourenço1, Noélia Duarte1, Isabel A C Ribeiro1

  • 1Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Avenida Prof. Gama Pinto, 1649-003 Lisboa, Portugal.

Pharmaceuticals (Basel, Switzerland)
|September 28, 2024
PubMed
Summary
This summary is machine-generated.

Microbial biosurfactants offer promising solutions to combat antibacterial resistance and biofilm formation. These biocompatible molecules can be used to create surfaces resistant to bacterial attachment, enhancing infection prevention strategies.

Keywords:
antifoulingantimicrobialantimicrobial releasebiosurfactantscontact killingstructure–activity relationship

More Related Videos

A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries
09:39

A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries

Published on: December 27, 2016

17.6K
Author Spotlight: An Antimicrobial Fabric Using Nano-Herbal Encapsulation of Essential Oils
07:47

Author Spotlight: An Antimicrobial Fabric Using Nano-Herbal Encapsulation of Essential Oils

Published on: April 7, 2023

7.9K

Related Experiment Videos

Last Updated: Jun 11, 2025

Enhanced Oil Recovery using a Combination of Biosurfactants
13:19

Enhanced Oil Recovery using a Combination of Biosurfactants

Published on: June 3, 2022

5.1K
A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries
09:39

A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries

Published on: December 27, 2016

17.6K
Author Spotlight: An Antimicrobial Fabric Using Nano-Herbal Encapsulation of Essential Oils
07:47

Author Spotlight: An Antimicrobial Fabric Using Nano-Herbal Encapsulation of Essential Oils

Published on: April 7, 2023

7.9K

Area of Science:

  • Microbiology
  • Biochemistry
  • Materials Science

Background:

  • Antibacterial resistance poses a significant global health threat, necessitating novel preventive strategies.
  • Microbial biosurfactants, including glycolipids and lipopeptides, are explored for their antimicrobial properties.
  • Biosurfactants are biocompatible, biodegradable, and non-toxic, making them suitable for health applications.

Purpose of the Study:

  • To review the physical and chemical characteristics of microbial biosurfactants.
  • To explore their antimicrobial and antibiofilm activities.
  • To discuss structure-activity relationships for developing novel antimicrobial approaches.

Main Methods:

  • Literature review focusing on microbial biosurfactants.
  • Analysis of antimicrobial and antibiofilm mechanisms.
  • Evaluation of surface modification strategies using biosurfactants.

Main Results:

  • Biosurfactants exhibit antimicrobial and antibiofilm properties, effective against difficult-to-treat infections.
  • Surface functionalization with biosurfactants can prevent bacterial attachment and biofilm formation on medical devices.
  • Both covalent bonding and surface absorption of biosurfactants demonstrate efficacy in reducing microbial load.

Conclusions:

  • Microbial biosurfactants represent a viable strategy to combat antibacterial resistance and biofilm-related infections.
  • Functionalizing surfaces with biosurfactants can enhance resistance to bacterial deposition and attachment.
  • Further research into biosurfactant structure-activity relationships can optimize their application in medical settings.