Related Experiment Video
Updated: Jun 11, 2025
10:23
Author Spotlight: Computing the Effects of a Local Radiofrequency Hyperthermia Intervention on Tumor Biomechanics
Published on: December 1, 2023
368
Experimental Validation of Realistic Measurement Setup for Quantitative UWB-Guided Hyperthermia Temperature
Alexandra Prokhorova1, Marko Helbig1
1Biosignal Processing Group, Technische Universität Ilmenau, 98693 Ilmenau, Germany.
Sensors (Basel, Switzerland)
|September 28, 2024
Summary
Non-invasive microwave imaging using ultra-wideband M-sequence technology accurately estimates tumor temperature during hyperthermia cancer treatment. This method aids in monitoring heat levels and protecting healthy tissues.
Area of Science:
- Medical Physics
- Biomedical Engineering
- Oncology
Background:
- Hyperthermia cancer treatment involves mild temperature increases (4-8 °C) to enhance radiation and drug efficacy.
- Accurate, non-invasive temperature monitoring is crucial to optimize hyperthermia and prevent healthy tissue damage.
Purpose of the Study:
- To present an ultra-wideband (UWB) M-sequence based microwave imaging approach for non-invasive temperature estimation during hyperthermia.
- To evaluate the method's performance in realistic neck cancer hyperthermia scenarios.
Main Methods:
- Utilized temperature-dependent dielectric properties of tissues and UWB imaging to estimate reflection coefficients.
- Employed Delay and Sum beamforming and Truncated Singular Value Decomposition for data processing.
- Conducted experiments involving tumor-mimicking materials to assess permittivity and temperature changes.
Main Results:
- Demonstrated qualitative and quantitative estimation of tissue dielectric permittivity.
- Successfully monitored real temperature changes in a tumor-mimicking phantom.
- Identified optimal frequency ranges and antenna configurations for temperature estimation.
Conclusions:
- The UWB M-sequence microwave imaging technique shows promise for accurate, non-invasive temperature monitoring in hyperthermia.
- The study provides insights into the method's capabilities and limitations for oncological applications.
Keywords:
M-sequence radar technologyMIMO systemexperimental validationhyperthermiaphantom measurementstemperature monitoringultra-wideband microwave imagingMore Related Videos
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