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Therapeutic uses of trace elements.

Clinics in Endocrinology and Metabolism

|August 1, 1985

Summary

This summary is machine-generated.

Trace elements are vital in medicine, treating diseases by interacting with biological molecules. Their diverse applications range from autoimmune disorders and cancer to gastrointestinal and central nervous system conditions.

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Area of Science:

Biochemistry
Pharmacology
Medicine

Background:

Trace elements possess therapeutic properties due to their ability to bind to macromolecules and interact with other elements.
Historically, metal compounds, particularly gold, have been used therapeutically for centuries, notably in treating rheumatoid arthritis.

Purpose of the Study:

To explore the multifaceted therapeutic applications of trace elements in human diseases.
To highlight the mechanisms of action and diverse clinical uses of trace elements.

Main Methods:

Review of historical and current therapeutic uses of trace elements.
Analysis of trace element properties, including macromolecular binding and elemental interactions.

Main Results:

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Trace elements are employed across a wide spectrum of diseases, including autoimmune disorders, cancer, gastrointestinal conditions, and central nervous system disorders.
Gold compounds remain significant in treating rheumatoid arthritis, with observed effects on immunological aspects relevant to other autoimmune conditions.
Metal complexes, such as platinum, show promise in cancer treatment with ongoing developments in less toxic compounds and administration protocols.
Trace elements play crucial roles in managing gastrointestinal acidity and nutrient availability, and lithium has shown significant efficacy in treating affective disorders.

Conclusions:

The broad therapeutic utility of trace elements underscores their importance in human health and disease management.
Further research into metal-based compounds and optimized administration protocols can expand their clinical applications, particularly in oncology and autoimmune diseases.