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Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...

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Updated: Jun 11, 2025

Synthesis of Aptamer-PEI-g-PEG Modified Gold Nanoparticles Loaded with Doxorubicin for Targeted Drug Delivery

Synthesis of Aptamer-PEI-g-PEG Modified Gold Nanoparticles Loaded with Doxorubicin for Targeted Drug Delivery

Published on: June 23, 2020

Polypeptides-Based Nanocarriers in Tumor Therapy.

Juhua You^1,2, Yifei Guo^1,2, Zhengqi Dong^1,2

¹School of Pharmacy, Heilongjiang University of Chinese Medicine, No. 24, Heping Road, Xiangfang District, Harbin 150040, China.

|September 28, 2024

Summary

This summary is machine-generated.

Peptides are versatile tools for cancer treatment, forming nanocarriers for targeted drug delivery systems (DDSs). These peptide DDSs effectively kill tumor cells and modulate immune responses, offering a promising cancer therapy outlook.

Keywords:

antitumor challenge drug delivery systems immunomodulation polypeptides-based nanocarriers

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Area of Science:

Biomedical Engineering
Oncology
Nanotechnology

Background:

Cancer is a global health challenge requiring novel therapeutic strategies.
Peptides offer advantages like biocompatibility, targeting, and low immunogenicity for drug delivery.
Peptides can enhance drug efficacy and modulate immune cells for cancer treatment.

Purpose of the Study:

To review the latest advancements in polypeptide-based nanocarriers for tumor therapy.
To focus on applications in direct tumor cell killing and immune cell regulation.
To analyze the transport function of peptides in nanocarriers and identify challenges and solutions.

Main Methods:

Literature review of recent research on peptide-based nanocarriers in cancer therapy.
Analysis of studies focusing on tumor cell targeting and immune modulation by peptide nanocarriers.
Examination of peptide functionality as carriers in drug delivery systems.

Main Results:

Peptide-based nanocarriers demonstrate significant potential in killing tumor cells.
These nanocarriers are effective in regulating immune cells for therapeutic benefit.
Peptides primarily function as carriers, facilitating targeted drug delivery.

Conclusions:

Peptide nanocarriers represent a promising avenue for innovative cancer treatment.
Addressing current limitations in peptide nano-delivery system construction is crucial for future development.
Further research into peptide-based strategies offers hope for improved cancer therapies.