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An Unconventional Case Study of Neoadjuvant Oncolytic Virotherapy for Recurrent Breast Cancer
Dubravko Forčić1,2, Karmen Mršić3, Melita Perić-Balja4
1Centre for Research and Knowledge Transfer in Biotechnology, University of Zagreb, 10000 Zagreb, Croatia.
Vaccines
|September 28, 2024
Summary
This case study shows oncolytic virotherapy using measles virus (MeV) and vesicular stomatitis virus (VSV) effectively shrank invasive breast cancer. The patient achieved successful surgery and remains recurrence-free, highlighting virotherapy
Area of Science:
- Oncology
- Virology
- Immunology
Background:
- Intratumoural oncolytic virotherapy is a potential strategy for debulking and downstaging inoperable tumors.
- Locally recurrent muscle-invasive breast cancer presents significant treatment challenges.
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