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[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Protocol for hydroxylating aryl chlorides catalyzed by photouranium with water under ambient conditions
Chengliang Li1, Leiyang Bai1, Xuefeng Jiang2
1Hainan Institute of East China Normal University, State Key Laboratory of Petroleum Molecular & Process Engineering, Shanghai Key Laboratory of Green Chemistry and Chemical Process, School of Chemistry and Molecular Engineering, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, P.R. China.
Abstract:
Here, we present a protocol for the hydroxylation of aryl chlorides catalyzed by photouranium with water under ambient conditions. We describe steps for gram-scale hydroxylation of 2'-chloroacetophenone using our self-designed continuous-flow photoreactor. We then detail procedures for obtaining 2'-hydroxyacetophenone using our self-designed rapid separation and purification instrument. This protocol is not suitable for polycyclic and heterocyclic aryl chlorides. For complete details on the use and execution of this protocol, please refer to Sun et al.1.
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