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Related Experiment Video

Updated: Jun 11, 2025

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models

Published on: March 1, 2015

Comorbidities associated with dysphagia after acute ischemic stroke.

Anel Karisik^1,2, Vincent Bader², Kurt Moelgg^1,2

¹VASCage - Centre on Clinical Stroke Research, Adamgasse 23, Innsbruck, Austria.

|September 28, 2024

Summary

Patients with multiple health conditions have a higher risk of post-stroke dysphagia. Early screening for swallowing problems is crucial for ischemic stroke patients, particularly those with several comorbidities.

Keywords:

Comorbidities Dysphagia Ischemic stroke Risk factors Swallowing impairment

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Published on: May 22, 2019

Area of Science:

Neurology
Internal Medicine
Clinical Research

Background:

Pre-existing comorbidities are known risk factors for post-stroke dysphagia.
This study aimed to investigate the prevalence of comorbidities in patients experiencing dysphagia following an ischemic stroke.

Purpose of the Study:

To determine the association between comorbidities and the occurrence of dysphagia in patients with acute ischemic stroke.
To identify specific comorbidities that increase the risk of post-stroke swallowing difficulties.

Main Methods:

Analysis of data from two large cohorts (STROKE-CARD trial and registry) of patients with acute ischemic stroke.
Dysphagia was assessed via clinical swallowing examination at hospital admission.
Comorbidities were quantified using the Charlson Comorbidity Index (CCI).

Main Results:

17.2% of 2054 ischemic stroke patients presented with dysphagia.
Dysphagia patients were older, experienced more severe strokes (higher NIHSS), and had significantly higher CCI scores.
Significant correlations were found between dysphagia and hypertension, atrial fibrillation, diabetes, non-smoking status, myocardial infarction, heart failure, peripheral arterial disease, chronic liver disease, and kidney disease. Associations with diabetes, peripheral arterial disease, kidney disease, liver disease, and overall CCI remained significant after adjustment.

Conclusions:

Multiple comorbidities significantly elevate the risk of developing post-stroke dysphagia.
Early and comprehensive screening for swallowing impairment is essential for acute ischemic stroke patients, especially those with multiple underlying health conditions.