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  11. Predictive Factors Associated With Health-related Quality Of Life In Patients With Colorectal Cancer In Iran: A Cross-sectional Study

Predictive factors associated with health-related quality of life in patients with colorectal cancer in Iran: a cross-sectional study

Amirmohammad Dahouri1, Mohammad Hasan Sahebihagh2, Neda Gilani3

  • 1Student Research Committee, Department of Community Health Nursing, Nursing & Midwifery Faculty, Tabriz University of Medical Sciences, Tabriz, Iran.

BMJ Open
|September 29, 2024

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View abstract on PubMed

Summary
This summary is machine-generated.

Health-related quality of life (HRQoL) is significantly impacted by factors like comorbidities, chemotherapy, colostomy, gender, living situation, and employment in colorectal cancer (CRC) patients. Addressing these aspects is crucial for improving patient care and outcomes.

Area of Science:

  • Oncology
  • Health Services Research
  • Quality of Life Studies

Background:

  • Colorectal cancer (CRC) significantly affects patients' health-related quality of life (HRQoL).
  • Understanding factors influencing HRQoL is vital for targeted interventions and improved patient care.

Purpose of the Study:

  • To identify key patient characteristics and clinical factors impacting HRQoL in CRC patients.
  • To provide evidence for healthcare providers to focus on specific patient subgroups.

Main Methods:

  • A cross-sectional study involving 251 colorectal cancer patients in Iran.
  • Health-related quality of life (HRQoL) was assessed using the SF-36 questionnaire.
  • Stepwise multiple regression analysis identified significant predictors of HRQoL.
Keywords:
AgingChronic DiseaseGastrointestinal tumoursONCOLOGY

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Main Results:

  • Overall HRQoL scores were found to be disturbed in the studied CRC patient population (47.22±16.78).
  • Significant predictors of lower HRQoL included comorbidities, colostomy, female gender, and unemployment.
  • Positive predictors of higher HRQoL included receiving only chemotherapy, living in their own house, and living in a city.

Conclusions:

  • Patient characteristics such as comorbidities, colostomy, unemployment, and female gender significantly predict HRQoL in CRC patients.
  • Healthcare providers should consider these factors to improve the quality of life for CRC patients.
  • Future research should explore interventions to mitigate the negative impact of CRC symptoms on HRQoL.
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