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Renal Injuries Induced by Supplements Containing Red Yeast Rice
Takeo Koshida1, Kanako Fukuhara1, Kenichiro Abe1
1Department of Nephrology, Juntendo University Urayasu Hospital, Japan.
Internal Medicine (Tokyo, Japan)
|September 29, 2024
Summary
Red yeast rice supplements can cause kidney damage, even in healthy individuals. Recent cases show acute kidney injury and worsening kidney disease after consumption.
Area of Science:
- Nephrology
- Dietary Supplements
- Cardiovascular Health
Background:
- Red yeast rice is a popular health food known for its cholesterol-lowering effects.
- Recent reports from Japan indicate a rise in kidney problems linked to red yeast rice supplements.
- This highlights a potential safety concern associated with its widespread use.
Purpose of the Study:
- To report cases of acute kidney injury associated with red yeast rice supplementation.
- To investigate the potential nephrotoxic effects of red yeast rice.
- To raise awareness among healthcare providers and consumers about these risks.
Main Methods:
- Case report analysis of patients experiencing renal impairment after taking red yeast rice supplements.
- Clinical assessment of renal function and kidney damage.
- Review of existing literature on red yeast rice and kidney health.
Main Results:
- Two cases are presented: a 42-year-old man with acute kidney injury and proximal tubular damage, and an 83-year-old woman with worsening diabetic kidney disease.
- Both patients developed renal dysfunction after consuming red yeast rice supplements.
- These findings suggest a causal link between red yeast rice intake and kidney injury.
Conclusions:
- Red yeast rice supplements may induce acute kidney injury.
- Individuals with pre-existing kidney conditions may be at higher risk of further renal function deterioration.
- Caution is advised when using red yeast rice supplements, especially for those with kidney disease.
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