[The influence of systemic factors on the prognosis of apical periodontitis]

Apical periodontitis (AP) is an inflammatory disease that occurs in the periapical tissue. The treatments of AP mainly include root canal therapy and endodontic surgery which promote the repair of periapical bone tissue by infections clearing and controlling inside or outside the root canal. The evaluation on efficacies of root canal therapy and endodontic surgery is mainly based on clinical and periapical imaging examinations, and the prognosis relates to multiple factors. The systemic factors of patients can directly or indirectly affect the healing of apical periodontitis. The present review summarizes the influence factors, including age, smoking habits, systemic diseases and systemic medication on the prognosis of apical periodontitis treatment, in order to increase the attention of clinicians.